The Independent Peptide Encyclopedia
Evidence-graded peptide reference reviewed by board-certified clinical pharmacists. Every article is source-linked to peer-reviewed research, independently written, and free from commercial influence.
Notable Peptides
BPC-157
BPC-157 is a synthetic peptide derived from stomach juice that may accelerate healing. Learn about uses, dosage protocols, side effects, legal status, and research evidence.
Semaglutide
Semaglutide is a GLP-1 receptor agonist approved for diabetes and weight management. Learn about uses, dosage protocols, side effects, legal status, and clinical evidence.
Tirzepatide
Tirzepatide is an FDA-approved dual GIP/GLP-1 receptor agonist for type 2 diabetes and weight loss. Learn about uses, dosage protocols, side effects, clinical trial data, and more.
TB-500
TB-500 is a synthetic peptide mimicking Thymosin Beta-4 that accelerates tissue repair, reduces inflammation, and enhances flexibility. Learn about uses, dosage protocols, side effects, legal status, and research evidence.
Retatrutide
Retatrutide is a triple receptor agonist (GLP-1, GIP, and glucagon) producing 24.2% weight loss in Phase 2 and up to 28.7% in Phase 3 (TRIUMPH-4). March 2026 TRANSCEND-T2D-1 results show HbA1c reductions of up to -2.0% and 16.8% weight loss in type 2 diabetes. Learn about dosage, the emerging dysesthesia safety signal, comparison vs semaglutide and tirzepatide, FDA approval timeline, and clinical evidence.
GHK-Cu
GHK-Cu is a naturally occurring copper peptide that may accelerate wound healing, rejuvenate skin, and modulate gene expression. Learn about uses, dosage protocols, side effects, legal status, and research evidence.
Ipamorelin
Ipamorelin: Selective GH secretagogue for enhanced body composition, recovery, and anti-aging. Doses 200-300mcg 1-3x daily. Minimal side effects, safe & well-tolerated.
CJC-1295
CJC-1295 is a synthetic growth hormone-releasing hormone analog that stimulates the pituitary to produce GH and IGF-1. Learn about uses, dosage protocols, side effects, legal status, and research evidence.
Explore all peptides→Peptide Science
Peptides: The Complete Evidence-Based Guide
The definitive guide to peptides — what they are, how they work, every major type, benefits, safety, and legality. Pharmacist-reviewed and evidence-based.
What Are Peptides? Complete Beginner's Guide
Learn what peptides are, how they work as cellular messengers, the different types, benefits, administration methods, safety considerations, and regulatory status.
Peptide Stacking Guide
Peptide stacking combines two or more peptides in coordinated protocols to achieve synergistic effects for muscle growth, fat loss, recovery, and cognitive enhancement. Learn the most effective stacks, dosing strategies, safety protocols, and monitoring guidelines.
Peptide Cycling
Learn when and why to cycle peptides. Understand cycling protocols for growth hormone secretagogues, healing peptides, and metabolic peptides to optimize results and avoid tolerance.
How to Safely Source Peptides: Avoiding Scams and Poor Quality
Learn how to safely source research peptides by verifying Certificates of Analysis, recognizing red flags, understanding purity metrics, and ensuring proper storage. A complete guide to avoiding scams and low-quality suppliers.
Explore all guides→Best Peptides For...
Weight Loss
Compare the most effective peptides for weight loss and fat loss. Evidence-based rankings of semaglutide, tirzepatide, retatrutide, AOD-9604, and more.
Recovery
Compare the best peptides for injury recovery, tissue repair, and healing. Evidence-based rankings of BPC-157, TB-500, GHK-Cu, and more with dosage protocols.
Muscle Growth
Compare the best peptides for muscle growth, recovery, and body composition. Evidence-based rankings of CJC-1295, Ipamorelin, GHRP-6, Sermorelin, and more.
Anti-Aging
Compare the best anti-aging peptides for longevity, skin health, cognitive function, and cellular repair. Evidence-based guide to Epithalon, SS-31, GHK-Cu, and more.
Skin Health
Compare the best peptides for skin health, anti-aging, collagen production, and wound healing. Evidence-based guide to GHK-Cu, BPC-157, KPV, and more.
Sleep
Compare the best peptides for sleep quality: Ipamorelin/CJC-1295, Selank, Epithalon. Evidence-based rankings with dosage protocols and mechanism explanations.
Gut Health
Compare the best peptides for gut health: BPC-157, KPV, GHK-Cu. Evidence-based rankings covering IBS, IBD, leaky gut, and intestinal repair with dosage protocols.
Joint Health
Compare the best peptides for joint pain, cartilage repair, and connective tissue health. Evidence-based rankings of BPC-157, TB-500, GHK-Cu, and more.
Explore all guides→Peptide Comparisons
Semaglutide vs Tirzepatide
Semaglutide vs tirzepatide compared: weight loss results, side effects, cost, and mechanisms. Evidence from STEP and SURMOUNT clinical trials.
BPC-157 vs TB-500
BPC-157 vs TB-500 compared head-to-head: mechanisms, dosage, efficacy, side effects, and when to use each. Plus: the Wolverine Stack protocol.
CJC-1295 vs Ipamorelin
CJC-1295 vs Ipamorelin explained: different mechanisms, why they stack so well together, dosing protocols, side effects, and which to choose.
Liraglutide vs Semaglutide
Liraglutide vs semaglutide compared: efficacy, dosing, side effects, cardiovascular data, and cost. SCALE vs STEP trials analyzed. Which GLP-1 agonist is right for you?
Semaglutide vs Retatrutide
Semaglutide vs retatrutide: how the proven GLP-1 agonist compares to the triple-agonist in clinical trials. Weight loss data, mechanisms, and what to expect.
Sermorelin vs CJC-1295
Sermorelin vs CJC-1295: clinical history, half-life, GH elevation, and which GHRH analog fits your protocol. The definitive comparison of the two most used options.
Ipamorelin vs GHRP-6
Ipamorelin vs GHRP-6 head-to-head: clean GH selectivity versus raw potency. Mechanism, dosing, side effects, and which GHRP fits your protocol.
Selank vs Semax
Selank vs Semax compared head-to-head: mechanisms, dosage, effects, and when to use each. Both developed at Russia's Institute of Molecular Genetics.
Explore all comparisons→Browse by Category
Weight Loss
AOD-9604, Liraglutide, Retatrutide, Semaglutide, Tirzepatide
Recovery
BPC-157, TB-500
Performance
CJC-1295, GHRP-2, GHRP-6, Ipamorelin, PT-141 (Bremelanotide), Sermorelin, Tesamorelin
Longevity
Epithalon (Epitalon), KPV, SS-31 (Elamipretide), Thymosin Alpha 1
Aesthetics
GHK-Cu, Melanotan II
Cognitive
Selank, Semax